SubtiBank SubtiBank
hxlB [2017-8-11 16:0:3]
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hxlB [2017-8-11 16:0:3]

6-phospho-3-hexuloisomerase
locus
BSU03450
pI
5.79
mw
19.82 kDa
protein length
185 aa Sequence Blast
gene length
555 bp Sequence Blast
function
ribulose monophosphate pathway for formaldehyde fixation
product
6-phospho-3-hexuloisomerase
essential
no
ec
5.3.1.27
synonyms
yckF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

    • Gene

    Coordinates
    374,603 → 375,160

    The protein

    Catalyzed reaction/ biological activity

  • D-arabino-hex-3-ulose 6-phosphate = D-fructose 6-phosphate (according to Swiss-Prot)

    • Protein family

  • PHI subfamily (according to Swiss-Prot)

    • Structure

  • [PDB|1M3S] [pubmed|15363790]

    • Expression and Regulation

    Operons

    genes
    [gene|BF480721B89661BFFE6632BB10C5F4DC29951784|hxlA]-[gene|FB0CEA291CA4EC5FB8410050E61B89EDBA1771F9|hxlB]
    description
    [Pubmed|10572115]

    regulatory mechanism

  • [protein|D9A187961CFB9496A6712E9E48AAD384357A3E1C|HxlR]: activation, [Pubmed|10572115], in [regulon|D9A187961CFB9496A6712E9E48AAD384357A3E1C|HxlR regulon]

    • regulation

  • induction by formaldehyde ([protein|search|HxlR]) [Pubmed|10572115]
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    Biological materials

    Mutant

  • MGNA-C056 (yckF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2054 NBRP B. subtilis, Japan]

    • References

  • 10572115,11468398,16428816,19170879,15363790